Nanotechnology: Cancer and Stem Cells

Cancer stem cells (CSCs) have been reported to play critical roles in the tumor initiation, propagation, and regeneration of cancer. Nano-size vehicles are employed to deliver drugs to target the CSCs for cancer therapy. Polymeric nanoparticles have been considered as the most efficient vehicles for drug delivery due to their excellent pharmacokinetic properties. The CSCs specific antibodies or ligands can be conjugated onto the surface of the nanoparticles to successfully target and eliminate CSCs.

In this review, we emphasize on the techniques of polymeric nanoparticles design for loading drug, and their potential application for CSCs targeting in cancer therapy.

  • Stem cell migration
  • Cell Migration and Durotaxis
  • Stem cell differentiation

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