Alexandra S Whale
Molecular and Cell Biology Team, UK
Biography
Alexandra completed her PhD in Molecular Biology in 2005 (University of Manchester), followed by a postdoctoral post at Imperial College London. Since 2009 she has worked in the Molecular and Cell Biology Team at LGC with a focus on nucleic acid metrology. Her area of expertise is trace detection of nucleic acids using digital PCR. She has published the use of digital PCR in a wide range of applications including quantification of microorganisms, detection of copy number variation and rare sequences in cancer. Her research also includs the use of digital PCR to investigate sampling bias in low concentration samples.
Abstract
Abstract : Detection of rare sequence variants using digital PCR